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What you need to know about Trazodone for dogs

Posted April 2, 2021

Depressed pug. Trazodone for dogs helps manage symptoms associated with separation anxiety, depression, or the need for excessive attention.
Trazodone for dogs helps manage symptoms associated with separation anxiety, depression, or the need for excessive attention.

Dogs are known for being loyal, loving companions, and it is no surprise that they fill our lives with joy. However, sometimes dogs can experience depression or anxiety due to a change in environment or other life events. When this occurs, the dog may exhibit decreased appetite, excessive barking, and excessive licking of objects around them.

Trazodone is an FDA-approved drug used successfully in humans for more than 50 years to treat insomnia and anxiety disorders. Recent studies have shown that Trazodone also has an antidepressant effect on dogs, helping them cope with demanding environmental changes, types of anxiety, and stressful events.

This article will discuss the essential information you need to know about using Trazodone for dogs.

What is Trazodone?

Trazodone hydrochloride (Desyrel®) belongs to a class of drugs called serotonin reuptake inhibitors (SSRIs). The FDA first approved it for use in humans in 1981. Trazodone is used to treat depression and anxiety disorders and chronic insomnia or other sleep problems. The most common side effects are nausea and dry mouth.

How does Trazodone work?

Trazodone is an antidepressant medication that is used to treat depression and anxiety disorders in humans. When taken, it helps regulate the brain’s neurotransmitters related to mood disorders such as serotonin, dopamine, and norepinephrine. The chemicals promote feelings of happiness and reward.

The drug works by altering the levels of serotonin in the brain. Serotonin is a brain chemical or neurotransmitter responsible for feelings of happiness, joy, and well-being. When there is not enough serotonin in the body, this can cause various symptoms such as depression, anxiety, and irritability. Trazodone helps increase serotonin levels in the brain, thus improving mood. Taking it can also help dogs stay asleep. If you aren’t sure how much to administer, you can check out the Trazodone for dogs dosage chart.

Trazodone benefits for dogs

Trazodone helps dogs manage symptoms associated with separation anxiety or the need for excessive attention.

According to studies published in the Journal of Small Animal Practice and the Journal of Veterinary Behavior Clinical Applications and Research, Trazodone successfully reduces separation anxiety symptoms in dogs.

Studies like one published in the Journal of Veterinary Behavior: Clinical Applications and Research show  Trazodone can help dogs with destructive behavior such as excessive barking and obsessively licking objects. 

Trazodone dosage for dogs

The recommended dose range is between 0.5 mg/kg to 3 mg/kg/day given orally. Give the drug 30 minutes before feeding your dog. You may increase the dosage to 6 mg/kg/day divided into two doses per day in some cases.

Adjust the dose depending on your pet’s response. Follow dosage recommendations from your veterinarian or certified veterinary technician (CVT). Consult your veterinarian if symptoms persist long-term because that could indicate a different underlying medical issue.

Trazodone side effects in dogs

Sad Golden Retriever hides under a blanket. Side effects of Trazodone for dogs can include hiding or avoiding contact with people and other dogs.
Side effects of Trazodone can include hiding or avoiding contact with people and other dogs.

Trazodone can cause side effects. The most common side effects seen in dogs are vomiting, diarrhea, and loss of appetite. Other side effects include:

  • Difficulty breathing or shortness of breath
  • Seizures
  • Extreme lethargy
  • Loss of coordination
  • Lack of interest in food or water
  • Hiding or avoiding contact with people and other dogs
  • Aggressive behavior

If you notice any of the above side effects in your dog, please consult your veterinarian, as it may require an adjustment in dosage or even discontinuation of treatment. As with any medication, it is essential to use caution when using Trazodone. Never give Trazodone to your dog without the approval of your veterinarian.

Do not give this drug to a dog allergic to trazodone hydrochloride or any of its inactive ingredients. Also, do not give this drug to a dog under the age of 12 weeks. Don’t treat pregnant or nursing dogs with this medication.

Xanax vs. Trazodone

Trazodone is a prescription medication you can use to treat anxiety in dogs. The drug is often compared to the drug Xanax. The two medications are similar but not identical. They both help reduce anxiety and stress in dogs, but they work in slightly different ways.

Xanax, also known as Alprazolam and Niravam, was created to treat panic disorders in humans. When given to dogs, the drug helps reduce anxiety and stress. It does this by increasing the amount of serotonin and norepinephrine in the brain. These chemicals are responsible for feelings of relaxation and well-being.

Because of its ability to produce anti-anxiety effects, Xanax is often used to help dogs experiencing separation anxiety, aggression issues, or who need a little extra boost when visiting the veterinarian or groomer.

Should you use Trazodone?

Our four-legged companions fill our lives with joy, which is why we would like to reciprocate and make their lives as stress-free as possible. Unfortunately, due to a variety of factors, our furry friends might become anxious and afraid. In this situation, there are plenty of ways to help reduce their anxiety levels, and Trazodone is one of the medications that often prove successful in this regard.

After reading this article, we hope you now understand how Trazodone works and how it could help your dog.

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Filed Under: Dog Health Tagged With: Health conditions, Separation anxiety

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